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Published on: June 23, 2023
Thrombotic thrombocytopenic purpura due to alcohol binge drinking
Doron Zamir1, Ilia Polychuck, Ilan Leibovitz
1Department of Internal Medicine D, Barzilai Medical Center, Ashkelon 78306, Israel.
Abstract:
Binge alcohol drinking is a pattern of alcohol abuse that is common among young males worldwide. It has been found to be associated with an increased likelihood of injury as a cause of death. Chronic alcohol abuse is known to cause some common hematological manifestations such as macrocytosis, thrombocytopenia, sideroblastic anemia, global marrow suppression, and folic acid deficiency anemia. We present a rare case involving an unusual and severe hematological manifestation of binge alcohol drinking: thrombotic thrombocytopenic purpura (TTP). The patient we present had severe and prolonged TTP necessitating prolonged treatment with plasmapheresis and plasma exchange. We discuss the relevant medical literature and the possible physiopathology of this complication.
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