Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

cpnDB: a chaperonin sequence database.

Janet E Hill1, Susanne L Penny, Kenneth G Crowell

  • 1National Research Council Plant Biotechnology Institute, Saskatoon, Saskatchewan S7N 0W9, Canada. Janet.Hill@nrc.ca

Genome Research
|August 4, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Infection with multiple strains of the Lyme disease bacterium in female mice can affect the strain-specific maternal antibody response in their offspring.

Ticks and tick-borne diseases·2026
Same author

Laboratory tests for bovine respiratory bacteria and antimicrobial resistance in commercial feedlot cattle: comparing culture, long-read metagenomics, and recombinase polymerase amplification.

Frontiers in microbiology·2026
Same author

Ligand-binding properties of substrate binding proteins of a maltose uptake system in <i>Gardnerella swidsinskii</i>.

Microbiology (Reading, England)·2026
Same author

Diagnostic sensitivity and specificity of metagenomic sequencing and qPCR for detection of viruses associated with bovine respiratory disease estimated using Bayesian latent class models.

Frontiers in veterinary science·2026
Same author

Prevalences of respiratory viruses and bacteria in Western Canadian commercial feedlot calves detected using a single metagenomic sequencing protocol vary during the first two weeks of arrival and by age group.

Frontiers in veterinary science·2026
Same author

Identification of genes that differentiate Mannheimia haemolytica genotypes 1 and 2 using a pangenome approach.

PloS one·2025
Same journal

High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV.

Genome research·2026
Same journal

Complete sequencing of medaka genomes reveals the architecture of centromeric satellites, giant mobile elements, and sex chromosomes.

Genome research·2026
Same journal

Convergence and conflict among telomere specialized transposons across 60 million years of Drosophilid evolution.

Genome research·2026
Same journal

A unified analysis of cell type- and trajectory-associated pathways in single-cell data using Phoenix.

Genome research·2026
Same journal

Resf1 is required for proper placental development and configuration of trophoblast cell-specific heterochromatin.

Genome research·2026
Same journal

Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture.

Genome research·2026
See all related articles

cpnDB is a new database featuring over 2000 curated sequences of the chaperonin 60 (cpn60) gene. This resource aids in microbial identification, phylogenetic studies, and understanding gene transfer.

Area of Science:

  • Microbiology
  • Molecular Biology
  • Bioinformatics

Background:

  • Type I chaperonins (CPN60) are essential molecular chaperones found across bacteria, archaea, and eukaryotic organelles.
  • CPN60 gene sequences are valuable for microbial phylogeny, diagnostics, and identification.
  • A conserved 549-567 bp region of the cpn60 gene is amplifiable using universal PCR primers.

Purpose of the Study:

  • To introduce cpnDB, a comprehensive, curated database of cpn60 gene sequences.
  • To provide a centralized resource for researchers utilizing cpn60 data in various studies.
  • To support microbial ecology, phylogenetic analysis, and diagnostic applications.

Main Methods:

  • Data compilation from public databases and collaborative networks.

Related Experiment Videos

  • Curation of approximately 2000 cpn60 sequence records.
  • Inclusion of archaeal Type II chaperonin sequences.

    • Main Results:

    • cpnDB contains over 2000 records spanning more than 240 bacterial, eukaryotic, and archaeal genera.
    • The database includes over 60 sequences for archaeal Type II chaperonins from 19 genera.
    • cpnDB is the largest curated collection of sequences for a protein-encoding gene.

    Conclusions:

    • cpnDB serves as a vital resource for researchers in microbial diagnostics, phylogeny, and ecology.
    • The database facilitates studies on lateral gene transfer and codon usage.
    • cpnDB is accessible online, built using open-source tools.