Related Experiment Video
Updated: Aug 11, 2026
Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1
M J Naidich1, M T Walker, N R Gottardi-Littell
1Department of Radiology, Northwestern Memorial Hospital and Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. m-naidich@northwestern.edu
Abstract:
We describe a case of cerebellar pleomorphic xanthoastrocytoma (PXA) occurring in a patient with neurofibromatosis type 1 (NF1). The histomorphology of this uncommon glial (astrocytic) neoplasm is discussed. The occurrence of this tumor within the posterior fossa is extremely rare. To our knowledge, this is the first reported case of a cerebellar PXA in a patient with NF1.
