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Updated: Aug 18, 2026

Cerebellar Regional Dissection for Molecular Analysis
Published on: December 5, 2020
Cerebellar paraganglioma
Richard A Prayson1, Ali Chahlavi, Mark Luciano
1Department of Anatomic Pathology, Cleveland Clinic Foundation, OH 44195, USA.
Abstract:
Paragangliomas arising as primary neoplasms in the intracranial portion of the central nervous system are relatively uncommon and only have been rarely reported. We report a case of apparent primary paraganglioma arising in the left cerebellar hemisphere in an 11-year-old girl who presented with a 6-month history of headaches. The tumor was marked by a nested architectural pattern (zellballen), delimited by S-100-positive sustentacular cells. Morphologic and immunohistochemical features of the neoplasm are discussed and literature is reviewed regarding involvement of the central nervous system by paraganglioma.
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