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Updated: Aug 23, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[New therapeutic approachs in melanoma]
L Mortier1, P Marchetti, L Gordower
1Services d'Oncologie médicale, Hôpital Erasme, ULB.
Abstract:
During the last decade, new insights in cellular and molecular biology have opened new avenues in cancer immunotherapy. Two distinct modalities have been developed: adoptive immunotherapy and anti-tumoral vaccination (active immunotherapy). We will first describe the main strategies of adoptive immunotherapy and then elaborate on the protocols of anti-tumoral vaccination against tumor associated antigens (TAA). In that context, we will pay peculiar attention on the pivotal role of dendritic cells (DC) as natural adjuvant.
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