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Neurosyphilis in newly admitted psychiatric patients: three case reports
Susan Saik1, John E Kraus, Alex McDonald
1Department of Internal Medicine, University of North Carolina, Chapel Hill, USA. susan.saik@ncmail.net
Background:
Neurosyphilis, also known as "general paresis of the insane," at one time accounted for a large portion of admissions to state psychiatric facilities. With the introduction of antibiotics, neurosyphilis is now considered very rare.
Method:
Chart review was performed on patients diagnosed with neurosyphilis who were admitted to a state psychiatric hospital in Raleigh, N.C., during 2002.
Results:
We identified 3 cases of confirmed neurosyphilis, representing 0.1% of adult admissions, diagnosed in newly admitted psychiatric patients. None of the patients were immunocompromised. Response to antibiotic treatment was poor.
Conclusions:
Given the increase in primary and secondary syphilis reported in the 1980s and early 1990s, routine screening of psychiatric patients for the presence of syphilis should be considered.
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