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Updated: Aug 23, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
Published on: January 31, 2025
Equal quality of life after limb-sparing or ablative surgery for lower extremity sarcomas
A Zahlten-Hinguranage1, L Bernd, V Ewerbeck
1Department of Orthopaedic Surgery, University of Heidelberg, Germany. anita.zahlten_h@ok.uni-heidelberg.de
Abstract:
This study investigated quality of life (QoL) and function of 124 patients with lower extremity sarcoma who underwent either amputation or limb-salvage surgery (LSS) in order to assess potential differences in subjective treatment outcome. The results reflect similar QoL in both treatment groups. However, in contrast to patients with LSS, who described QoL in terms of a high physical performance status with sports and recreational activities, amputees' QoL was strongly associated with their social acceptability. High QoL in amputees brings into question the expectations held with time-consuming advanced technical skills for LSS by physicians.