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Published on: September 25, 2018
Clinicopathological analysis of clinical N0 peripheral lung cancers with a diameter of 1 cm or less
Y Moriya1, A Iyoda, K Hiroshima
1Department of Thoracic Surgery, Graduate School of Medicine, Chiba University, Inohana, Chuo-ku, Chiba, Japan.
Background:
The appropriateness of limited resection for small-sized lung cancer continues to be debated. It is not yet clear whether tumor size alone is a reliable indicator for limited resection.
Methods:
From 1980 to 2002, 27 patients with clinical N0 peripheral lung cancers having diameters of 1 cm or less underwent pulmonary resection. Clinicopathological features of these cases were reviewed retrospectively.
Results:
Histological analysis showed that there were 23 cases of adenocarcinoma (81.5 %), two large cell carcinomas (7.4 %), and two carcinoid tumors. Twenty-two cases were classified as pathological stage 1, one was stage II, and four were stage III. Four patients (14.8 %) had lymphatic vessel invasion, three (11.1 %) had lymph node metastasis, and two (7.4 %) had intrapulmonary metastasis. The 5-year disease-free survival rate was 76.6 %.
Conclusions:
It is impossible to predict the effectiveness of an intentional limited resection for lung cancer using only tumor size.
