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[Severe acute asthma]
Jean-Luc Pagani1, Mauro Oddo, Marie-Denise Schaller
1Division des Soins Intensifs de Médecine, Département de Médecine Interne, CHUV, 1011 Lausanne. jean-luc.pagani@hospvd.ch
Revue Medicale De La Suisse Romande
|August 6, 2004
Summary
Acute severe asthma requires advanced treatment beyond standard care. Mechanical ventilation strategies, including permissive hypercapnia and non-invasive ventilation, are crucial for managing respiratory distress and reducing mortality in severe cases.
Area of Science:
- Pulmonology
- Critical Care Medicine
Context:
- Acute severe asthma presents as a life-threatening exacerbation resistant to initial treatment.
- Severe lung hyperinflation and respiratory distress characterize these critical events.
Purpose:
- To review the pathophysiological principles of acute severe asthma.
- To outline current medical treatments and mechanical ventilation strategies for this condition.
Summary:
- Conventional treatment includes oxygen, inhaled beta2-agonists, systemic corticosteroids, and magnesium sulfate.
- Mechanical ventilation, particularly controlled hypoventilation with permissive hypercapnia, is vital when initial therapies fail.
- Non-invasive ventilation and helium-oxygen mixtures are considered adjunctive therapies.
Impact:
- Highlights the importance of specific ventilatory strategies to prevent complications from mechanical ventilation.
- Aims to improve patient outcomes by detailing advanced management approaches for acute severe asthma.