Related Experiment Video

Updated: Aug 23, 2026

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
06:38

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Published on: March 11, 2016

Cardiac cyclic variation of integrated backscatter in hypertension and dialysis patients

Harun Akar1, Ceyhun Ceyhan, Yavuz Yenicerioglu

  • 1Department of Nephrology, Adnan Menderes University Medical School, Aydin, Turkey. hakar2002@hotmail.com

Journal of Nephrology
|August 6, 2004
PubMed

Insights

Cyclic variation of myocardial-integrated backscatter (CV-IB) shows altered myocardial structure in end-stage renal disease (ESRD) and essential hypertension (EH) patients. CV-IB values were lower in EH patients than controls and ESRD patients, and lower in ESRD patients than controls.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Nephrology

Background:

  • Cyclic variation of myocardial-integrated backscatter (CV-IB) is a non-invasive method for assessing myocardial contractile function.
  • Limited data exists on CV-IB in patients with end-stage renal disease (ESRD).

Purpose of the Study:

  • To investigate and compare CV-IB in essential hypertensive (EH) patients, ESRD patients, and healthy controls.
  • To assess myocardial ultrasonic tissue characteristics using CV-IB.

Main Methods:

  • Compared 40 EH patients, 24 ESRD patients, and 10 healthy controls using 2D-Doppler echocardiography.
  • Analyzed CV-IB at the interventricular septum (IVS) and left ventricular (LV) posterior wall (PW) during systole and diastole.

Main Results:

  • EH patients had significantly higher blood pressure than ESRD patients and controls.
  • Left ventricular mass index (LVMI) was elevated in both EH and ESRD patients compared to controls.
  • CV-IB values were significantly lower in EH patients compared to ESRD patients and controls, and lower in ESRD patients compared to controls.

Conclusions:

  • CV-IB provides valuable parameters for evaluating myocardial structure in EH and ESRD patients.
  • Further research is warranted to fully elucidate the role and implications of CV-IB in ESRD patients.
Abstract

More Related Videos

Ultrasonic Assessment of Myocardial Microstructure10:53

Ultrasonic Assessment of Myocardial Microstructure

Published on: January 14, 2014

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Assessing Blood pressure using a doppler ultrasound01:19

Assessing Blood pressure using a doppler ultrasound

To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment: