[The pathogenetic role of the infection component in children with lymphadenopathy under modern conditions]

Apart from lymphadenopathy types observed in well-known diseases (oncology and hematology pathologies, systemic lesions of connective tissues, tuberculosis, brucellosis, infection mononucleosis, toxoplasmosis, AIDS and other specific processes), there is an extensive group of lymphadenopathy (up to 70% of all disease cases), whose cause cannot be diagnosed by using the routine examination schemes. This was reflected in the diagnosis of "lymphadenopathy of unverified etiology" according to the MKB-1 now in force. Investigations of the role (in etiopathogenesis) of unverified lymphadenopathy types as observed in children with the infection component as well as optimization of their diagnosis and treatment schemes are elucidated in the paper. It is substantiated, on the basis of published data and authors' independent research, that some of lymphadenopathy types of unverified etiology are related with such opportunistic infections, like clamidiosis, mycoplasmosis, herpes simplex and cytomegalovirus infection. The above stated is, primarily, compatible with the tropicity of such infections' agents to the lymphoid tissue and/or with their possible lymphogenic spread as well as with polymorphism of clinical signs conditioned by the discussed infection agents.