Related Experiment Video
Updated: Aug 23, 2026

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
Published on: January 7, 2018
Risk factors for low birth weight: a review
Javier Valero De Bernabé1, Trinidad Soriano, Romana Albaladejo
1Department of Obstetrics and Gynecology, Hospital Universitario Santa Cristina and Medicine School of Autonomous University of Madrid, Spain.
Insights
Low birth weight (LBW) remains a significant predictor of infant mortality globally. Despite existing preventive interventions targeting risk factors, the incidence of LBW has not shown a decrease.
Area of Science:
- Perinatal Medicine
- Public Health
- Reproductive Epidemiology
Background:
- Low birth weight (LBW) is a primary determinant of infant mortality, with global incidence around 17%.
- Incidence varies significantly, from 19% in developing nations to 5-7% in developed countries.
- In Spain, the incidence was approximately 5.7% between 1980-1989.
Purpose of the Study:
- To analyze the persistent incidence of low birth weight.
- To review known risk factors and the efficacy of current interventions.
Main Methods:
- Review of epidemiological data on low birth weight incidence.
- Analysis of established risk factors including socio-economic status, maternal health, and lifestyle.
- Evaluation of the impact of existing prenatal interventions.
Main Results:
- Low birth weight is strongly linked to intrauterine malnutrition stemming from placental circulation issues.
- Key risk factors identified include socio-economic determinants, pre-existing or gestational medical conditions, and maternal lifestyle choices.
- Despite available interventions, a reduction in LBW incidence has not been observed.
Conclusions:
- Low birth weight remains a critical public health challenge with persistent incidence.
- Existing interventions targeting known risk factors have not effectively reduced LBW rates.
- Further research into novel prevention strategies is warranted to address this ongoing issue.
Abstract:
Low birth weight (LBW) is one of the main predictors of infant mortality. The global incidence of LBW is around 17%, although estimates vary from 19% in the developing countries (countries where it is an important public health problem) to 5-7% in the developed countries. The incidence in Spain in the decade 1980-1989 was about 5.7%. LBW is generally associated with situations in which uterine malnutrition is produced due to alterations in placental circulation. There are many known risk factors, the most important of which are socio-economic factors, medical risks before or during gestation and maternal lifestyles. However, although interventions exist to prevent many of these factors before and during pregnancy, the incidence of LBW has not decreased.
Related Concept Videos
Factors Affecting Illness
For instance, risk factors are connected to illness, disability,...
Development of the Oral Microbiota
Regression Toward the Mean
Factors affecting Blood pressure
Physiological Factors:
Development of Human Microbiota
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
