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Accidental ecstasy poisoning in a toddler
Abian Montesdeoca Melian1, Guillermo Burillo-Putze, Candelaria Gonzalez Campo
1Pediatric Intensive Care Unit, Hospital Universitario de Canarias, Tenerife, Spain.
Insights
Accidental ingestion of Ecstasy (MDMA) in toddlers can cause severe symptoms like seizures and hyperthermia. However, with supportive care, young children can fully recover from this type of drug poisoning.
Area of Science:
- Pediatric Toxicology
- Emergency Medicine
- Pharmacology
Background:
- Accidental ingestion of recreational drugs like Ecstasy (3,4-methylenedioxymethamphetamine or MDMA) poses a significant risk to young children.
- Pediatric cases of MDMA intoxication are rare, and clinical presentations and outcomes require further elucidation.
Purpose of the Study:
- To report a case of a toddler with severe symptoms following accidental Ecstasy ingestion.
- To review existing literature on Ecstasy poisoning in infants and toddlers.
- To highlight the clinical presentation and management of pediatric MDMA toxicity.
Main Methods:
- Case report of a 14-month-old child with accidental Ecstasy ingestion.
- Clinical observation including vital signs, symptoms, and laboratory analysis (urine and serum drug levels).
- Review of three previously reported cases of Ecstasy poisoning in toddlers and infants.
Main Results:
- The child presented with generalized convulsions, hyperthermia, hypertension, tachycardia, and tachypnea 40 minutes after ingestion.
- Urine amphetamine/methamphetamine levels were elevated (>16 mg/L), and serum MDMA was 0.591 mg/L.
- The child recovered fully with supportive care and benzodiazepines, despite initial critical symptoms.
Conclusions:
- Pediatric Ecstasy intoxication can lead to severe, life-threatening symptoms, often presenting initially with seizures.
- Toddlers and infants may experience faster symptom onset compared to adults.
- Despite initial severity, pediatric MDMA poisoning appears to have a good prognosis with appropriate medical management and emphasizes the need for caution regarding accidental ingestion.
Abstract:
A child of 14 months accidentally swallowed a portion of an Ecstasy pill. Forty minutes after ingestion, he started a generalized convulsion. He also presented hyperthermia (38 degrees C), hypertension, tachycardia (130 bpm), ventricular extrasystoles, tachypnea (50 rpm), and mydriasis. At the hospital 5 hours later, the urine levels of amphetamine/metamphetamine were >16 mg/L. He was treated with general support measures and benzodiazepines intravenously and admitted to the pediatric intensive care unit. During the first 12 hours, he continued with hypertension, tachycardia, and long periods of trigeminy, without hemodynamic repercussion. He was discharged fully recovered. Gas chromatography/mass spectrometry analysis (8 hours after ingestion) showed a serum level of 3,4 methylenedioximethylamphetamine (MDMA) of 0.591 mg/L. The 3 cases described in the literature have shown a good evolution of Ecstasy poisoning in toddlers and infants, despite an initial critical situation. Regarding adults, the toddler intoxication seems to present symptoms sooner (20 to 30 minutes), having as an initial manifestation convulsions. However, great care must be taken on accidental ingestion of these attractive design pills.
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