Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Current research in avian chemotherapy.

Lucio J Filippich¹, Bruce G Charles

¹School of Veterinary Science, University of Queensland, St. Lucia, Queensland, 4072 Australia. L.Filippich@uq.edu.au

The Veterinary Clinics of North America. Exotic Animal Practice

|August 7, 2004

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pharmacometrics in Australasia-Twenty Years of Population Approach Group of Australia and New Zealand.

CPT: pharmacometrics & systems pharmacology·2019

Same author

Preliminary Evidence for Enhanced Thymine Absorption: A Putative New Phenotype Associated With Fluoropyrimidine Toxicity in Cancer Patients.

Therapeutic drug monitoring·2018

Same author

Erratum to: Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

Cancer chemotherapy and pharmacology·2017

Same author

Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

Cancer chemotherapy and pharmacology·2017

Same author

Towards a test to predict 5-fluorouracil toxicity: Pharmacokinetic data for thymine and two sequential metabolites following oral thymine administration to healthy adult males.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2015

Same author

Breastmilk-Saliva Interactions Boost Innate Immunity by Regulating the Oral Microbiome in Early Infancy.

PloS one·2015

Pharmacokinetic data for chemotherapy drugs in birds is scarce. Recent studies in cockatoos provide crucial information on cisplatin and carboplatin, enabling better avian cancer treatment and safety trials.

Area of Science:

Veterinary Medicine
Pharmacology
Avian Oncology

Background:

Chemotherapy is vital in avian oncology, but its use is often empirical due to a lack of pharmacokinetic data in birds.
Understanding drug behavior in avian species is essential for effective and safe cancer treatment.

Purpose of the Study:

To investigate the pharmacokinetic profile of platinum analogs, specifically cisplatin and carboplatin, in avian species.
To establish a foundation for evidence-based clinical and toxicity trials in avian oncology.

Main Methods:

Pharmacokinetic analysis of cisplatin and carboplatin administered to Sulfur-crested cockatoos.
Data collection on drug absorption, distribution, metabolism, and excretion in the study subjects.

Main Results:

Related Experiment Videos

The pharmacokinetic profiles of cisplatin and carboplatin were successfully determined in Sulfur-crested cockatoos.
This data provides essential information previously unavailable for these chemotherapeutic agents in birds.

Conclusions:

The reported pharmacokinetic data for cisplatin and carboplatin in cockatoos is a significant advancement for avian oncology.
This research paves the way for more informed clinical applications and toxicity assessments of these platinum analogs in birds.