Related Experiment Video
Updated: Aug 23, 2026

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model
Published on: April 2, 2021
Risk factors of threshold retinopathy of prematurity
Sourabh Dutta1, Subina Narang, Anil Narang
1Department of Pediatrics, Division of Neonatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India 160012. sourabhdutta@yahoo.co.in
Objective:
To determine the risk factors which predispose to the development of threshold retinopathy of prematurity among patients of retinopathy of prematurity.
Methods:
The ROP clinic records of a 3 year period were retrospectively studied to identify babies with threshold ROP (T-ROP) and sub-threshold ROP (ST-ROP). Various antenatal and perinatal risk factors, neonatal morbidity and therapeutic interventions were compared between the 2 groups.
Results:
Of the total of 108 babies, 55 had T-ROP and 53 had ST-ROP. On univariate analysis, packed cell transfusions for anemia, double volume exchange transfusions (DVET), number of DVET, ventilation, gestational age
Conclusion:
Administration of blood products increases the risk of developing T-ROP among patients who have ROP. There is a need to exercise caution in the use of blood products in premature newborns.
Related Concept Videos
Diabetic Retinopathy
Photoreceptors and Visual Pathways
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...

