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Outcome of cancer patients admitted to the intensive care unit (ICU)
Marwan Ghosn1, Chaker Kanso, Joseph Kattan
1Department of Hematology-Oncology, Hôtel-Dieu de France Hospital, Beirut, Lebanon.
Insights
Cancer patient survival in the ICU is significantly impacted by length of stay. This study found that factors like age or mechanical ventilation did not affect mortality rates for these critically ill patients.
Area of Science:
- Oncology
- Critical Care Medicine
- Epidemiology
Background:
- Critically ill cancer patients admitted to the Intensive Care Unit (ICU) present unique challenges.
- Understanding survival rates and influencing factors is crucial for improving patient outcomes.
Purpose of the Study:
- To determine the causes of ICU admission for cancer patients.
- To analyze survival rates and identify factors influencing survival in this population.
Main Methods:
- Retrospective study of 181 cancer patients admitted to HDF hospital's ICU between January 1998 and June 1999.
- Data collected on patient demographics, reasons for admission (surgical vs. medical), tumor type, and need for mechanical ventilation (MV).
- Survival analysis conducted to assess mortality at various time points and identify prognostic factors.
Main Results:
- The overall mortality rate was high, reaching 83% at last follow-up.
- The duration of ICU stay was the sole significant factor influencing patient mortality.
- Age, cancer type (solid tumors vs. hematological malignancies), and the requirement for mechanical ventilation did not significantly impact survival rates.
Conclusions:
- ICU admission for cancer patients is associated with poor prognosis.
- Prolonged ICU length of stay is a critical predictor of mortality.
- Further research may explore interventions to mitigate risks associated with prolonged ICU stays in cancer patients.
Abstract:
This is a retrospective study aiming to determine the cause, the survival and the factors influencing survival in cancer patients admitted to an ICU. Between January 1998 and June 1999, 181 cancer patients were admitted to the ICU of HDF hospital (a general academic hospital of 300 beds). One hundred fifteen patients were admitted after surgery and 66 for medical reasons. Among the non-surgical group, 37 had solid tumors and 29 had hematological malignancies. Most of non-surgical patients were admitted for respiratory or infectious complications due to their disease or treatment-related (59 patients). Among the non-surgical group of patients, 44 required mechanical ventilation (MV). The mortality rate was 41% during ICU recovery, 62% during the hospitalization period, 73% at 2 months from discharge and 83% at last follow-up. The duration of stay in the ICU was the only factor affecting mortality. Age, disease type and MV did not influence the mortality rate in this population.
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