Analysis of pulmonary venous flow velocity patterns in hypertensive hearts: its complementary value in the...

Although the Doppler mitral flow velocity pattern changes in accordance with the degree of left ventricular diastolic dysfunction, it is "normalized" in the presence of heart failure. In this study the pulmonary venous flow velocity pattern was characterized in 43 hypertensive patients with and without heart failure to clarify whether analysis of the pulmonary venous flow velocity pattern provides complementary information in the interpretation of the mitral flow velocity pattern. The mitral flow velocity pattern in 32 hypertensive patients without heart failure was characterized by decreases in the peak early diastolic filling velocity (E) and the ratio of E to peak filling velocity at atrial contraction. The mitral flow velocity pattern was "normalized" in 11 patients with heart failure, with no differences in any mitral flow velocity pattern indexes as compared with 24 normal subjects. The pulmonary venous flow velocity pattern in hypertensive patients without heart failure was characterized by a decreased peak diastolic forward flow velocity (D) and an increased ratio of peak systolic forward flow velocity (S) to D (S/D ratio). In patients with heart failure, D was higher and the S/D ratio was lower compared with hypertensive patients without heart failure (p less than 0.01, p less than 0.01) and normal subjects (p less than 0.01, p less than 0.01). Thus the pulmonary venous flow velocity pattern appeared to be more reliable than the mitral flow velocity pattern in differentiating subgroups of patients with hypertension. Analysis of the pulmonary venous flow velocity pattern in conjunction with the mitral flow velocity pattern provides important and complementary information in the interpretation of the mitral flow velocity pattern in hypertensive patients with and without heart failure.