Related Experiment Video
Updated: Aug 23, 2026

Crystallization and In Situ Room Temperature Data Collection Using the Crystallization Facility at Harwell and Beamline VMXi, Diamond Light Source
Published on: March 8, 2024
Two distinct approaches to crystallization results-recording databases
A M Hassell1, T J Harrocks, E H Dashman
1Bioanalytical and Structural Chemsitry Department, Glaxo Research Institute, Research Triangle Park, NC 27709, USA.
Abstract:
Two different systems for recording crystallization results are described. Both programs are written in Microsoft Excel. Results can be entered either as text or numerical scores. In each system, one can search or query on the results, macromolecule name, experimental parameters, etc. and correlate these to specific crystallization conditions or trends in the crystallizations. Such information is valuable when optimizing crystal growth conditions and determining new crystallization parameters to test. XTAL RES is a Macintosh program that is linked to PCRYSTAL (software used to enter details of the crystallization experiments) through an Oracle database on a VAX network. A second system, the Electronic Notebook, was designed as a 'stand-alone' Excel application running under Microsoft Windows.
Related Concept Videos
Recrystallization: Solid–Solution Equilibria
Crystal Growth: Principles of Crystallization
Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent – the...
Determination of Crystal Structures
Precipitation Processes

