Signaling aptamers for monitoring enzymatic activity and for inhibitor screening

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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

Razvan Nutiu1, Jasmine M Y Yu, Yingfu Li

  • 1Departments of Biochemistry and Chemistry, McMaster University, 1200 Main Street West, Hamilton, L8N 3Z5 Ontario, Canada.

Chembiochem : a European Journal of Chemical Biology
|August 10, 2004
PubMed
Abstract

No abstract available in PubMed .

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Enzyme Inhibition01:30

Enzyme Inhibition

Inhibitors are molecules that reduce enzyme activity by binding to the enzyme. In a normally functioning cell, enzymes are regulated by a variety of inhibitors. Drugs and other toxins can also inhibit enzymes. Some inhibitors bind to the enzyme’s active site, while others inhibit enzymatic activity by binding to other sites on the protein structure.