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Smallpox vaccine: "non-take" responses in previously vaccinated adults
Georgia Thomas1, Elizabeth Frenzel, Hend Hanna
1Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston 77030, USA.
Abstract:
This small, retrospective study of laboratory workers who received smallpox vaccine showed a strong correlation between "non-take" reactions and the presence of prior vaccination scars. Although we cannot exclude technique and vaccine potency as causes, the association we observed may indicate that these workers are displaying residual immunity to smallpox.
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