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Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging
Published on: February 10, 2012
Imaging of congenital coronary anomalies with multislice computed tomography
Andrew R Deibler1, Ronald S Kuzo, Matthias Vöhringer
1Department of Radiology, Mayo Clinic College of Medicine, Jacksonville, Fla 32224, USA.
Insights
Multislice computed tomographic (MSCT) coronary angiography effectively images congenital coronary anomalies, aiding clinical decisions. This technique accurately identifies the origin and course of abnormal coronary arteries in patients.
Area of Science:
- Cardiovascular Imaging
- Congenital Heart Disease
- Radiology
Background:
- Congenital coronary anomalies are rare but can lead to significant clinical complications.
- Accurate imaging of coronary artery origins and courses is crucial for diagnosis and management.
- Multislice computed tomographic (MSCT) coronary angiography offers a non-invasive imaging modality.
Purpose of the Study:
- To evaluate the utility of retrospectively gated MSCT coronary angiography in characterizing congenital coronary anomalies.
- To describe a single-center experience with MSCT for imaging these anomalies.
Main Methods:
- Retrospective review of 9 patients with congenital coronary anomalies diagnosed via invasive angiography.
- Analysis of MSCT imaging data by two experienced observers.
- Classification of the origin and proximal course of abnormal coronary arteries.
Main Results:
- MSCT successfully identified the origin and course of coronary arteries in 8 out of 9 patients.
- Specific anomalies visualized included anomalous right coronary arteries, anomalous left circumflex coronary arteries, and single coronary arteries.
- One patient showed a normal but anteriorly displaced right coronary artery origin.
Conclusions:
- Retrospectively gated MSCT coronary angiography is a valuable tool for imaging congenital coronary anomalies.
- MSCT can accurately characterize the proximal course of abnormal coronary arteries, similar to other advanced imaging techniques.
- This modality aids in clinical decision-making for patients with congenital coronary anomalies.
Objective:
To describe a single-center experience of using retrospectively gated multislice computed tomographic (MSCT) coronary angiography for imaging congenital coronary anomalies.
Patients And Methods:
We retrospectively reviewed the clinical information and imaging studies for 9 patients diagnosed as having congenital coronary anomalies on invasive, selective coronary angiography between February 2001 and October 2003 at the Mayo Clinic in Jacksonville, Fla. Two experienced observers classified by consensus the origin and proximal course of the abnormal coronary arteries as seen on MSCT.
Results:
In 1 patient, MSCT showed a normal but extremely anterior origin of the right coronary artery from the right aortic sinus of Valsalva. In the other 8 patients, the origin and course of 4 anomalous right coronary arteries, 2 anomalous left circumflex coronary arteries, and 2 single coronary arteries were recognized easily on MSCT.
Conclusion:
Similar to electron beam computed tomography and magnetic resonance imaging, widely available MSCT can characterize the proximal course of congenitally abnormal coronary arteries and thus aid in clinical decision making for patients with such anomalies.
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