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[Expression of chemokine-like factor 2(CKLF2) mRNA in rat myocardium with hypertrophy]
Hong-kun Ren1, Tao Hong, Jie Jiang
1Department of cardiology, Peking University First Hospital, Beijing 100034,China.
Objective:
To investigate the expression of CKLF2 mRNA in the rat myocardium with hypertrophy.
Methods:
Rat abdominal aorta was constricted by operation to make myocardium hypertrophy in the hypertrophy group and the control group was subjected to the sham-operation. The CKLF2 mRNA expressions were tested by competitive polymerase chain reaction (CPCR).
Results:
Compared to the control-group, the expression of CKLF2 mRNA of hypertrophy-group significantly increased on the 17th day after operation, and decreased to the control level on the 45th day.
Conclusion:
The expression of rCKLF2 mRNA in rat myocardium with hypertrophy significantly increased in early days of hypertrophy.
