Related Experiment Video
Updated: Aug 23, 2026
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Impact of intraoperative autotransfusion on RBC's in vivo half-life]
Xi-hui Li1, Ming-li Zhang, Chun-li Zhang
1Department of Cardiovascular Surgery, Peking University First Hospital, Beijing 100034, China. daizhuang98@163.com
Objective:
To explore the changes of in vivo half-life of processed erythrocytes following intraoperative autotransfusion(IAT) in off-pump coronary artery bypass grafting(CABG).
Methods:
From November 2003 to January 2004,20 consecutive patients undergoing scheduled off-pump CABG were randomly divided into experimental group and control group. Intra-operative autotransfusion was used in the experimental group. The samples were drawn immediately after the saving procedure in the experimental group and immediately after anesthesia introduction through central venous catheter in the control group. A single isotope technique ((51)Cr) was used to determine in vivo half-life of the RBCs in the two groups.
Results:
There was no significant difference in in vivo half-life between the two groups.
Conclusion:
The in vivo half life of processed erythrocytes following intraoperative autotransfusion ZITI-3000 Cell saving system has not changed significantly in off-pump CABG.
Related Concept Videos
01:15Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
02:45Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...