Related Experiment Video
Updated: Aug 23, 2026

Bidirectional Retroviral Integration Site PCR Methodology and Quantitative Data Analysis Workflow
Published on: June 14, 2017
Internipple distance and internipple index
Alexander K C Leung1, C Pion Kao, Reginald S Sauve
1Department of Pediatrics, and the Asian Medical Centre, an affiliate with the University of Calgary Medical Clinic, Calgary, Alberta, Canada.
Insights
This study established reference standards for internipple distance and internipple index in Chinese children. Findings highlight ethnic variations in nipple placement, crucial for accurate assessment.
Area of Science:
- Anthropometry
- Pediatric Health
- Human Anatomy
Background:
- The internipple distance and internipple index are key anthropometric measures.
- Understanding these measurements is vital for assessing nipple placement and potential developmental variations.
- Ethnic differences in anthropometry are well-documented and necessitate population-specific reference data.
Purpose of the Study:
- To determine the internipple distance and internipple index in a large cohort of Chinese children.
- To establish age- and sex-specific reference values for these measurements in Chinese pediatric population.
- To investigate the relationship between internipple index and age in Chinese children.
Main Methods:
- A cross-sectional study involving 3,290 healthy Chinese children aged 0-18 years.
- Standardized anthropometric measurements of internipple distance and chest circumference were performed.
- The internipple index was calculated using the formula: (internipple distance cm * 100) / chest circumference cm.
Main Results:
- Both internipple distance and chest circumference showed a positive correlation with age.
- The internipple index was highest in neonates and decreased significantly by age four.
- The internipple index remained relatively stable from age four onwards, with a gradual decrease in females after age 11.
Conclusions:
- The internipple index provides a practical method for evaluating nipple spacing.
- Significant ethnic variations exist in the internipple index, underscoring the need for specific reference standards.
- Accurate assessment of nipple placement requires utilizing appropriate, population-specific reference data.
Objective:
To determine the internipple distance and internipple index in Chinese children.
Methods:
The internipple distance and chest circumference were measured in 3,290 healthy Chinese children (1,715 males and 1,575 females) aged birth to 18 years seen at the Asian Medical Centre. The internipple distance and chest circumference were obtained at the end of expiration whenever possible, with a standard nonstretch tape measure graduated in millimeters with the arms hanging relaxed alongside the body. Patients under two years of age were measured supine and those over two years of age standing. The internipple distance was measured between the centers of both nipples, and the chest circumference was measured across the internipple line. The internipple index was calculated according to the formula: internipple distance (cm) multiplied by 100 and divided by chest circumference (cm).
Results:
The internipple distance and chest circumference increased with age. The internipple index was highest in the neonatal period (26.4 +/- 1.6 for males and 26.3 +/- 2 for females), and decreased steadily until the age of four years (23.8 +/- 1.2 for males and 23.8 +/- 1.4 for females), and thereafter was relatively constant through the age of 18 years in males and the age of 11 years in females. In females, the internipple index decreased gradually from the age of 11 years to 18 years.
Conclusions:
While internipple index is a more practical way to assess nipple placement, there are ethnic differences in the internipple index. Proper reference standards should be used in the assessment whether the nipples are closely or widely spaced.
Related Concept Videos
Interference: Path Lengths
Two special sources may be considered when they are in phase. This can be easily achieved by feeding the two sources from the same source. An example would be synchronizing the two speakers by feeding them with the same source, such as the sound waves produced by a tuning fork. This setup ensures that the two sources have the same frequency and are...
Interval Level of Measurement
Data measured using the interval scale are similar to ordinal level data because they have a definite arrangement. However, in the interval level of measurement, the differences between data values are meaningful even though the data does not have a starting point.
Temperature is measured using the interval scale. It is measurable data, and the difference between the...
Types of Semiconductors
Distance Problem
Inequalities
Series and Parallel Inductors
For a series connection of N inductors, each carrying the same current, applying Kirchhoff's voltage law unveils a crucial relationship. Substituting the expression for...

