Appendiceal tumour--retrospective clinicopathological analysis

Area of Science:

• Gastroenterology
• Surgical Oncology
• Pathology

Background:

• Appendiceal tumours are uncommon and frequently diagnosed during emergency surgery.
• Their presentation can be challenging, complicating timely decision-making.

Purpose of the Study:

• To analyze the spectrum of appendiceal tumours.
• To discuss their clinicopathological characteristics, diagnostic methods, surgical management, and patient outcomes.
• To review existing literature on appendiceal neoplasms.

Main Methods:

• Retrospective analysis of 1646 appendectomies performed over 10 years.
• Inclusion of 12 patients diagnosed with appendiceal tumours.
• Review of clinical data, histopathology, surgical procedures, and outcomes.

Main Results:

• Twelve appendiceal tumours identified (0.72%): 8 carcinoid, 2 mucinous (mucocele), and 2 adenocarcinoma.
• Carcinoid tumours typically presented as acute appendicitis, diagnosed post-appendectomy.
• Surgical approach varied: appendectomy for most carcinoids, hemicolectomy for cystadenoma near the base or adenocarcinoma.

Conclusions:

• Carcinoid tumours are the most frequent appendiceal neoplasms, often mimicking acute appendicitis.
• Appendectomy is sufficient for localized carcinoid tumours, but right hemicolectomy is indicated for appendiceal cystadenoma or adenocarcinoma.
• Prognosis is favorable for carcinoid and cystadenoma, but poor for disseminated appendiceal adenocarcinoma.