Related Experiment Video

Updated: Aug 23, 2026

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
07:10

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies

Published on: January 7, 2019

Pain: a common symptom in human immunodeficiency virus-infected Thai children

R Lolekha1, P Chanthavanich, K Limkittikul

  • 1Queen Sirikit National Institute of Child Health, Bangkok, Thailand.

Acta Paediatrica (Oslo, Norway : 1992)
|August 12, 2004
PubMed

Insights

Pain is common in Thai children with human immunodeficiency virus (HIV) infection, affecting 44% of those studied. Many infected children with pain did not receive adequate treatment, highlighting a need for better pain management in their care.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Pain Management

Background:

  • Pain is a significant issue for children living with human immunodeficiency virus (HIV).
  • Understanding pain prevalence and characteristics in this population is crucial for effective care.
  • Previous research on pain in pediatric HIV patients in Thailand is limited.

Purpose of the Study:

  • To determine the prevalence and characteristics of pain experienced by children infected with HIV in Thailand.
  • To compare pain reporting between HIV-infected children and healthy children.
  • To assess the adequacy of pain management in this cohort.

Main Methods:

  • A cross-sectional study was conducted at a pediatric HIV/AIDS outpatient clinic in Bangkok, Thailand.
  • Sixty-one HIV-infected children (aged 4-15) and an equal number of healthy controls participated.
  • Structured interviews with children and caregivers were used to collect data on pain experiences.

Main Results:

  • Forty-four percent of HIV-infected children reported pain, significantly higher than the 13% in the control group (OR=5.3).
  • Seven percent of HIV-infected children experienced chronic pain, often located in the abdomen, lower limbs, or head.
  • Children in advanced HIV clinical stages (B and C) reported more pain than those in earlier stages (N and A) (OR=4.0).
  • Only 44% of HIV-infected children experiencing pain received analgesic medication.

Conclusions:

  • Pain is a prevalent and often undertreated issue in Thai children with HIV/AIDS.
  • There is a significant gap in pain identification, assessment, and management for these children.
  • Systemic integration of adequate pain management strategies into routine care is recommended.
Abstract

More Related Videos

Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity07:15

Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity

Published on: November 22, 2021

Peptide-based Identification of Functional Motifs and their Binding Partners14:28

Peptide-based Identification of Functional Motifs and their Binding Partners

Published on: June 30, 2013

Related Concept Videos

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...