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Updated: Aug 23, 2026

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
57Fe NMR spectroscopy of ferrocenes bearing pi-acceptor substituents
Bernd Wrackmeyer1, Oleg L Tok, Anahid Ayazi
1Laboratorium für Anorganische Chemie der Universität Bayreuth, D-95440 Bayreuth, Germany. b.wrack@uni-bayreuth.de
Abstract:
Ferrocene derivatives bearing pi-acceptor substituents in 1- or 1,1'-positions such as carbonyl group(s) (1, 2), a sulfinyl group (4) or boryl group(s) (5, 6, 9) and related [3]ferrocenophanes (3, 7, 10, 12, 13) and a [4]ferrocenophane (8) were studied by 57Fe NMR spectroscopy. The deshielding effect of the respective pi-acceptor substituent can be partially or fully compensated by distortion of the ferrocene geometry. Both aspects become apparent by comparing delta57Fe data of the [n]ferrocenophanes with those of related non-cyclic derivatives.
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