Related Experiment Video
Updated: Aug 23, 2026
Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography
Published on: January 17, 2025
Craniofacial growth in the ferret (Mustela putorius furo)--a cephalometric study
Tailun He1, Stavros Kiliaridis
1Department of Orthodontics, Faculty of Odontology, The Sahlgrenska Academy at Göteborg University, Box 450, SE-405 30 Gothenburg, Sweden. tailun.he@odontologi.gu.se
Objective:
When suggesting the ferret as a valid laboratory model in craniofacial research, it is essential to know about its normal craniofacial growth.
Design:
Sixteen ferret kits (eight male and eight female) were selected for the present investigation. Serial lateral and dorsoventral cephalograms were taken on each animal at a mean age of 25, 35, 55, 80 and 300 days. The cephalograms were then digitised and the coordinates of 33 landmarks were derived on each set of cephalograms. Thirty-four variables were then calculated on each set of cephalograms by computer image programs with the coordinate data. Results were analysed statistically, and the craniofacial growth pattern and related sexual dimorphism were described in three perspectives: lateral and dorsoventral viscero- and neurocranium, and lateral mandible.
Findings:
In both sexes, the viscero- and neurocranium follow an orderly pattern of expansive growth in three dimensions. The growth of the mandible is mainly characterised by an anteroposterior elongation of the mandibular body, an enlargement of the coronoid process, and an increase in height of the alveolar process. The growth rate varies with site. Craniofacial growth in ferrets starts to slow down and finally ceases earlier in female than in male animals.
