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[Complex regional pain syndrome. Current status].

Paola Andrea Díaz-Zuluaga1, Ricardo Plancarte-Sánchez, Antonio César Tamayo-Valenzuela

  • 1Departamento de Hemato-Oncología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, D. F. paoladiazco@yahoo.com

Cirugia Y Cirujanos
|August 18, 2004
PubMed
Summary

Complex regional pain syndrome (CRPS) is a complex neurological disorder following trauma, marked by severe pain and sensory changes. Current diagnostic and treatment strategies for CRPS lack sufficient evidence, highlighting a need for further research.

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Area of Science:

  • Neurology
  • Pain Medicine
  • Autonomic Nervous System Research

Context:

  • Complex regional pain syndrome (CRPS) arises after trauma, with or without nerve injury.
  • It presents with spontaneous pain, hyperalgesia, allodynia, altered sensation, and autonomic dysfunction.
  • CRPS involves both acute inflammatory and chronic neuropathic changes, affecting spinal and supraspinal pathways.

Purpose:

  • To review the characteristics, diagnosis, and treatment of Complex Regional Pain Syndrome (CRPS).
  • To highlight the challenges in establishing diagnostic criteria due to symptom variability.
  • To assess the current evidence for diagnostic and therapeutic interventions in CRPS.

Summary:

  • CRPS is characterized by pain, sensory abnormalities, and autonomic dysfunction, linked to central nervous system changes.

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  • Diagnostic difficulties arise from the syndrome's diverse symptomatology.
  • Phentolamine sympathetic blockade is a common diagnostic tool, but treatment effectiveness remains insufficiently evidenced.

    • Impact:

    • This review underscores the complexity of CRPS, impacting patient quality of life.
    • It identifies gaps in diagnostic certainty and treatment efficacy for CRPS.
    • Further research is crucial to develop evidence-based diagnostic and therapeutic approaches for CRPS management.