Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Models of human sleep regulation.

D G Beersma1

  • 1Department of Psychiatry and Zoological Laboratory, Graduate School of Behavioral and Cognitive Neuroscience, University of Groningen, The Netherlands. d.g.m.beersma@biol.rug.nl

Sleep Medicine Reviews
|August 18, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spectral analysis of the sleep EEG of depressed patients before and after total sleep deprivation.

Acta neuropsychiatrica·2016
Same author

The prevalence of seasonal affective disorder (SAD) in The Netherlands.

Acta neuropsychiatrica·2016
Same author

A longitudinal study of sleep deprivation responses in depression; The variability is highly related to diurnal mood variability.

Acta neuropsychiatrica·2016
Same author

Extraocular light therapy in winter depression: a double-blind placebo-controlled study.

Biological psychiatry·2001
Same author

Seasonal changes in 24-h patterns of suicide rates: a study on train suicides in The Netherlands.

Journal of affective disorders·2001
Same author

Seasonal variation in suicides: hidden not vanished.

The British journal of psychiatry : the journal of mental science·2001
Same journal

The misclassification of periodic limb movement disorder: A systematic review applying research diagnostic criteria.

Sleep medicine reviews·2026
Same journal

Letter to the editor: Attrition as a proxy for acceptability in digital CBTi: Conceptual limitations and methodological priorities.

Sleep medicine reviews·2026
Same journal

Association of media use with sleep of children and adolescents: an umbrella review.

Sleep medicine reviews·2026
Same journal

Beyond respiratory control in COMISA: Towards precision phenotyping in PAP-based therapies.

Sleep medicine reviews·2026
Same journal

The potential of clustering methods for pre-test triage in sleep medicine: A systematic review.

Sleep medicine reviews·2026
Same journal

Assessing the effects of non-invasive transcranial electrical stimulation (tACS and tDCS) on electrophysiological sleep parameters - a systematic review.

Sleep medicine reviews·2026
See all related articles

Sleep deprivation, both Non-REM and REM, triggers specific rebounds, indicating essential physiological needs. Sleep

Area of Science:

  • Sleep science
  • Neuroscience
  • Chronobiology

Background:

  • Non-REM and REM sleep deprivation induce specific rebound phenomena, suggesting these sleep stages fulfill critical physiological needs.
  • Impaired performance following sleep deprivation highlights a likely recovery function of sleep.
  • Nocturnal sleep timing in humans is primarily influenced by the circadian pacemaker in the hypothalamus affecting sleep propensity.

Purpose of the Study:

  • To review and discuss models of sleep regulation, focusing on the interaction between homeostatic recovery processes and the circadian pacemaker.
  • To examine refinements and alternative models to the established two-process model of sleep regulation.
  • To evaluate theoretical and data-fitting aspects of various sleep regulation models.

Main Methods:

Related Experiment Videos

  • Review of existing literature on sleep deprivation, sleep regulation models, and circadian rhythms.
  • Analysis and discussion of the two-process model of sleep regulation as a foundational framework.
  • Exploration of theoretical refinements and alternative conceptual models for sleep regulation.

Main Results:

  • Evidence suggests distinct physiological needs met by Non-REM and REM sleep, evidenced by rebound phenomena.
  • Sleep deprivation impairs performance, supporting a crucial recovery function of sleep.
  • The timing of sleep is strongly regulated by the interplay between circadian and homeostatic processes.

Conclusions:

  • The two-process model provides a basis for understanding sleep regulation, integrating homeostatic and circadian influences.
  • Further refinements and alternative models are necessary to fully capture the complexities of sleep regulation.
  • Understanding these interactions is key to comprehending sleep's role in physiological recovery and performance.