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Ionic hemolysis behavior of erythrocytes in rats of both sexes

A Marossy1, I Bracoková, E Dorko

  • 1Department of Physiology, Medical Faculty of PJ Safarik University, Tr. SNP 040 66 Kosice, Slovak Republic. marossy@pobox.sk

Clinical Hemorheology and Microcirculation
|August 18, 2004
PubMed

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Lifecycle of Erythrocytes01:22

Lifecycle of Erythrocytes

Erythrocytes, also known as red blood cells, constantly move through blood capillaries. As a result, they damage their plasma membrane due to the continuous friction. Typically, after 100 to 120 days, erythrocytes become rigid and fragile as they wear out. As they pass through small vessels in the spleen and liver, they can get trapped and break apart into fragments.
The resident phagocytic macrophages deal with these damaged cells by engulfing them and separating their globin and heme groups.