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Updated: Jul 15, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[TOAST subtyping of acute ischemic stroke]
Heng Zhou1, Yong-jun Wang, Su-xiang Wang
1Department of Neurology, Beijing Tiantan Hospital Capital University of Medical Sciences, Beijing 100050, China.
Zhonghua Nei Ke Za Zhi
|August 18, 2004
Summary
Large-artery atherosclerosis is the most common cause of ischemic stroke in Chinese individuals, according to the Trial of Org 10 172 in Acute Stroke Treatment (TOAST) criteria. This study analyzed 300 patients to classify stroke subtypes.
Area of Science:
- Neurology
- Epidemiology
- Vascular Medicine
Context:
- Ischemic stroke presents diverse etiological characteristics globally.
- Understanding stroke subtypes is crucial for targeted prevention and treatment strategies.
- The Trial of Org 10 172 in Acute Stroke Treatment (TOAST) criteria provide a standardized classification system.
Purpose:
- To characterize the etiological subtypes of ischemic stroke in a Chinese population.
- To apply the TOAST criteria for classifying ischemic stroke based on clinical data and neuroimaging.
- To investigate the relative incidence of different ischemic stroke subtypes in Chinese patients.
Summary:
- A study of 300 Chinese ischemic stroke patients classified subtypes using TOAST criteria.
- Results indicated large-artery atherosclerosis (40.0%) and lacunar stroke (31.3%) were most prevalent.
- Cardio embolism (12.3%), other etiologies (5.0%), and undetermined etiology (11.4%) comprised the remainder.
- No significant gender-based differences in subtype distribution were observed.
Impact:
- Highlights the high prevalence of large-artery atherosclerosis as a cause of ischemic stroke in China.
- Provides essential epidemiological data for public health initiatives and clinical management of stroke in this demographic.
- Informs future research on the specific risk factors and therapeutic interventions for major stroke subtypes in Chinese populations.
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