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Updated: Aug 23, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
Pediatric urologic oncology: bladder, prostate, testis
1University of Pittsburgh and Department of Urology, Children's Hospital of Pittsburgh, 4A-424 Desoto Wing, 3705 5th Avenue, Pittsburgh, PA 15213, USA. wuhy@chp.edu
Abstract:
Although treatment for bladder, prostate, and testis cancer comprises a large part of adult urologic practice, the tumors that affect these organs in children are rare. Rhabdomyosarcoma,which affects the bladder, prostate, vaginal, and paratesticular areas,is treated with a combination of surgery, chemotherapy, and radiation. Most transitional cell carcinomas of the bladder and prepubertal testis tumors are managed surgically owing to the low stage at presentation. Application of the technical advances learned in adults with tumors of the bladder, prostate, and testis, combined with an understanding of the difference in tumor biology, helps urologists improve the treatment of these tumors in children.
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