Related Experiment Video

Updated: Aug 23, 2026

CO2-Lasertonsillotomy Under Local Anesthesia in Adults
05:07

CO2-Lasertonsillotomy Under Local Anesthesia in Adults

Published on: November 6, 2019

Subtenons lidocaine injection for postoperative pain relief after strabismus surgery in children: A prospective

Richard M Sheard1, Jodhbir S Mehta, John-S Barry

  • 1The Moorfields Eye Hospital, London, United Kingdom.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|August 18, 2004
PubMed

Insights

Subtenons lidocaine injections significantly reduced immediate postoperative pain in children undergoing strabismus surgery. This intervention effectively managed pain without increasing the need for systemic analgesia.

Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Pain Management

Background:

  • Previous pilot study suggested subtenons lidocaine reduces immediate postoperative pain after pediatric strabismus surgery.
  • A prospective, randomized controlled trial was conducted to validate these findings.

Purpose of the Study:

  • To evaluate the efficacy of subtenons lidocaine in reducing postoperative pain in children undergoing strabismus surgery.
  • To assess the impact on the need for additional systemic analgesia.

Main Methods:

  • Children undergoing primary or reoperation for strabismus were recruited.
  • The treatment group received 1 ml of 2% lidocaine in the subtenons space before conjunctival closure.
  • Parental pain assessment using an objective tool was conducted over 4 hours postoperatively.

Main Results:

  • A subtenons lidocaine injection significantly reduced pain at 0 hours post-surgery (P = 0.0056).
  • The total 4-hour postoperative pain score was significantly lower in the lidocaine group (P = 0.0381).
  • No significant difference in the need for systemic analgesia was observed between groups (P = 0.307).

Conclusions:

  • Intraoperative subtenons lidocaine injection effectively reduces postoperative pain in children's strabismus surgery.
  • The intervention shows significant pain reduction within the first postoperative hour.
  • Subtenons lidocaine did not alter the requirement for systemic analgesia.
Abstract

Related Concept Videos

Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Chemistry and Structure-Activity Relationship01:30

Local Anesthetics: Chemistry and Structure-Activity Relationship

Local anesthetics (LAs) are drugs that induce a temporary loss of sensation in a limited body area, preventing pain. Cocaine was the first local anesthetic discovered in the late 19th century. Cocaine is a benzoic acid ester obtained from the leaves of coca shrubs and was often used for its psychotropic effects. Cocaine was first isolated in 1860 by Albert Niemann. Sigmund Freud studied the physiological actions of cocaine. Carl Koller later introduced it into clinical practice in 1884 as a...
Local Anesthetics: Pharmacokinetics01:13

Local Anesthetics: Pharmacokinetics

The potency and duration of action of local anesthetics (LAs) are determined by their pharmacokinetics. Pharmacokinetics describes how LAs are absorbed, distributed, metabolized, and eliminated from the body. When administered to the vascular tissues, LAs are quickly absorbed and enter the systemic circulation, reducing their localized effects. Adding vasoconstrictors such as epinephrine to LAs reduces their absorption into the systemic circulation, making them clinically effective. The...