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[Portal vein thrombosis in a patient with lowered protein S level]
L Fechner1, E Lotterer, W E Fleig
1Klinik und Poliklinik für Innere Medizin I, Martin-Luther-Universität Halle-Wittenberg, Halle/Saale.
History And Clinical Findings:
In a 39-year-old man with increasing spasmodic epigastric pain, nausea and vomiting, varices of the esophagus and the gastric fundus were found endoscopically.
Investigations:
A portal vein thrombosis and a consecutive thrombosis of the splenic vein were diagnosed by colour Doppler sonography and angio CT. A protein S deficiency (59 %) was found to be the underlying illness.
Treatment And Course:
The thrombosis and the resulting clinical symptoms completely resolved shortly after starting therapeutic heparinization. For six months, the patient has been without complaints or clinical symptoms.
Conclusion:
Hence, an isolated protein S deficiency can be the cause for a portal vein thrombosis.
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