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Updated: Aug 23, 2026

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
[Hyperbaric oxygenation with low excess pressure implemented in the pressure chamber within the complex intensive
Abstract:
An attempt was made to apply the hyperbaric oxygenation (HBO) in victims with craniocerebral trauma. HBO sessions were carried out in a low excess pressure (0.2 ATA) with the simultaneous use of clonidin as antihinoxant and antioxidant (2 mkg/kg), which was done for the purpose of eliminating or decreasing the pronouncement degree of additional stimulation of the lipid-peroxidation processes by hyperbaric oxygen (such processes were already stimulated by combined trauma). Requirements are substantiated on the need in a differential approach to the indication of the HBO course even if it is implemented in the described (sparing) regime. If there is a negative body response to the HBO effect, which happened in 8 of 18 persons according to our observations, the HBO course must be interrupted.
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