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Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...

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[Herpes zoster in Germany. A retrospective analyse of SHL data].

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Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

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[Varicella-zoster virus infections].

H M Lilie¹, S W Wassilew

¹Dermatologische Klinik, Klinikum Krefeld, Lutherplatz 40, 47805 Krefeld, Germany. lilie@klinikum-krefeld.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete

|August 19, 2004

Summary

Varicella-zoster virus (VZV) causes chickenpox and shingles. Early antiviral therapy for shingles in elderly patients can reduce the risk and duration of postherpetic neuralgia.

Area of Science:

Virology
Dermatology
Neurology

Context:

Varicella-zoster virus (VZV) causes primary varicella (chickenpox), a common childhood illness.
VZV reactivation leads to herpes zoster (shingles), a neurodermal disease.
Shingles often presents with severe pain and can lead to postherpetic neuralgia.

Purpose:

To review the role of antiviral therapy in managing VZV infections, particularly herpes zoster.
To highlight the importance of early intervention in preventing complications like postherpetic neuralgia.

Summary:

Primary VZV infection manifests as varicella, typically in children.
Herpes zoster, a VZV relapse, involves nerve-specific lesions and significant pain.
Early antiviral treatment for herpes zoster in elderly patients is crucial for reducing postherpetic neuralgia risk and duration.

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Impact:

Antiviral therapy, combined with pain management, is recommended for all elderly patients diagnosed with herpes zoster.
Timely treatment can significantly improve patient outcomes and quality of life by mitigating shingles-related pain and complications.