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Updated: Aug 22, 2026

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment
Published on: September 14, 2013
The prevention of Clostridium difficile associated diarrhoea in hospital
1Cardiff and Vale NHS Trust.
Abstract:
The number of health care-associated infections has increased over the years and generated a lot of interest and concern. The attention tends to be focused on methicillin-resistant Staphylococcus aureus (MRSA), but the less publicised Clostridium difficile is a growing problem. It increases length of hospital stay, causes significant morbidity in patients, affects nurses' workloads, adds to the cost of cleaning, laundry and disposables, and can lead to ward closures. All NHS trusts in England are now required to report C. difficile-associated diarrhoea (CDAD) in all patients over 65 years of age (National Clostridium Difficile Standards Group, 2003).
Insights
Clostridium difficile infections are a growing concern in healthcare settings, leading to longer hospital stays and increased costs. Increased reporting of C. difficile-associated diarrhoea in elderly patients is now mandated.
Area of Science:
- Infectious Diseases
- Hospital Epidemiology
- Public Health
Background:
- Healthcare-associated infections (HAIs) are a rising concern.
- Methicillin-resistant Staphylococcus aureus (MRSA) receives significant attention, but Clostridium difficile presents a growing challenge.
- Clostridium difficile infections (CDI) lead to increased patient morbidity, extended hospital stays, and significant financial burdens.
Purpose of the Study:
- To highlight the increasing problem of Clostridium difficile infections in healthcare settings.
- To emphasize the impact of CDI on patient outcomes, healthcare staff, and hospital resources.
- To note the mandatory reporting requirements for C. difficile-associated diarrhoea (CDAD) in England.
Main Methods:
- This study is a review of the literature and current concerns regarding Clostridium difficile.
- Data on the impact of CDI on hospital stays, patient morbidity, and costs are discussed.
- Analysis of the implications of mandatory reporting for healthcare trusts.
Main Results:
- Clostridium difficile infections contribute significantly to patient morbidity and prolonged hospital stays.
- CDI impacts nursing workloads, increases cleaning and supply costs, and can necessitate ward closures.
- All NHS trusts in England are now required to report CDAD in patients over 65.
Conclusions:
- Clostridium difficile represents a significant and growing threat within healthcare environments.
- Effective management and reporting of CDI are crucial for patient safety and healthcare system efficiency.
- The mandatory reporting of CDAD underscores the seriousness of this infection.
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