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Intestinal imaging of children with acute rotavirus gastroenteritis

Dorsey Bass1, Eileen Cordoba, Cornelia Dekker

  • 1Department of Pediatrics, Stanford University, Stanford, California 94305, USA. dorseybass@hotmail.com

Journal of Pediatric Gastroenterology and Nutrition
|August 21, 2004
PubMed

Insights

Abdominal ultrasound detected increased ileal wall thickness in infants with rotavirus gastroenteritis. This finding may indicate inflammation and could aid in evaluating rotavirus vaccines.

Area of Science:

  • Pediatric Gastroenterology
  • Medical Imaging
  • Infectious Diseases

Background:

  • Rotavirus gastroenteritis is a common pediatric illness.
  • Assessing gastrointestinal inflammation in infants non-invasively is challenging.

Purpose of the Study:

  • To evaluate distal small bowel morphology and motility in infants with rotavirus gastroenteritis.
  • To utilize non-invasive, non-ionizing imaging techniques for assessment.

Main Methods:

  • Prospective observational study of five infants with symptomatic rotavirus infection.
  • Real-time magnetic resonance imaging (MRI) and ultrasound were performed during acute illness and convalescence (5-9 weeks later).

Main Results:

  • Three of five infants showed increased ileal wall thickness on ultrasound during acute infection compared to convalescence.
  • Mesenteric lymph node size and peristaltic activity (assessed by MRI) remained similar between phases.

Conclusions:

  • Abdominal ultrasound can identify ileal wall thickening in infants with rotavirus infection, suggesting potential ileal inflammation.
  • These imaging findings may be valuable for assessing morphologic responses to rotavirus vaccines.
Abstract

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