Related Experiment Video
Updated: Jul 12, 2026

Engineering Adherent Bacteria by Creating a Single Synthetic Curli Operon
Published on: November 16, 2012
Colicin A and colicin E1 lysis proteins differ in their dependence on secA and secY gene products
1Centre de Biochimie et de Biologie Moléculaire du C.N.R.S., Marseille, France.
Abstract:
The export of colicin A and of colicin E1 is not equally affected in both secA and secY mutants of Escherichia coli: release of colicin A occurs slowly while that of colicin E1 is blocked. Processing and functioning of Cal, the colicin A lysis protein, seem to be slightly or not at all modified in these mutants, whereas synthesis and assembly of CelA, the colicin E1 lysis protein, are highly inhibited. These variations observed in the dependence of the two lysis proteins on secA and secY gene products are interpreted as being either the cause or the consequence of the differences observed in their rate of biogenesis.
Related Concept Videos
Overview of Secretory Vesicles
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
Gram-negative Bacterial Protein Secretion Systems
Inducible Operons: lac Operon
Stringent Response in E. coli
Bacterial Toxins
Bacterial Gastroenteritis

