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Intra-abdominal tumors in children

Ghazala Hanif1

  • 1Department of Pathology, King Edward Medical College, Lahore. koool@brain.net.pk

Insights

Neuroblastoma and Wilms' tumor are the most common pediatric intra-abdominal tumors. Most cases occur in children under five, with a slightly higher incidence in males.

Area of Science:

  • Pediatric Oncology
  • Surgical Pathology
  • Childhood Cancers

Background:

  • Intra-abdominal tumors represent a significant group of pediatric malignancies.
  • Understanding their histopathological patterns is crucial for diagnosis and treatment planning.

Purpose of the Study:

  • To analyze the histopathological spectrum of intra-abdominal tumors in children under 16 years of age.
  • To correlate tumor types with patient age and sex.

Main Methods:

  • A descriptive study analyzing histopathological and demographic data.
  • Involved 264 cases of intra-abdominal tumors in patients under 16 years.
  • Data collected over a 5-year period (1997-2002) in Lahore.

Main Results:

  • Neuroblastoma (29.6%) and Wilms' tumor (25.1%) were the most frequent diagnoses.
  • Non-Hodgkin's lymphoma (15.5%), germ cell tumors (9%), and hepatoblastoma (9%) were also significant.
  • The majority of patients (77.2%) were younger than 5 years, with a male predominance (1.1:0.9 ratio).

Conclusions:

  • Intra-abdominal tumors in children exhibit a distinct histopathological pattern.
  • Early age of onset (under 5 years) and male sex are associated with higher incidence.
Abstract