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Intra-abdominal tumors in children
1Department of Pathology, King Edward Medical College, Lahore. koool@brain.net.pk
Insights
Neuroblastoma and Wilms' tumor are the most common pediatric intra-abdominal tumors. Most cases occur in children under five, with a slightly higher incidence in males.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
- Childhood Cancers
Background:
- Intra-abdominal tumors represent a significant group of pediatric malignancies.
- Understanding their histopathological patterns is crucial for diagnosis and treatment planning.
Purpose of the Study:
- To analyze the histopathological spectrum of intra-abdominal tumors in children under 16 years of age.
- To correlate tumor types with patient age and sex.
Main Methods:
- A descriptive study analyzing histopathological and demographic data.
- Involved 264 cases of intra-abdominal tumors in patients under 16 years.
- Data collected over a 5-year period (1997-2002) in Lahore.
Main Results:
- Neuroblastoma (29.6%) and Wilms' tumor (25.1%) were the most frequent diagnoses.
- Non-Hodgkin's lymphoma (15.5%), germ cell tumors (9%), and hepatoblastoma (9%) were also significant.
- The majority of patients (77.2%) were younger than 5 years, with a male predominance (1.1:0.9 ratio).
Conclusions:
- Intra-abdominal tumors in children exhibit a distinct histopathological pattern.
- Early age of onset (under 5 years) and male sex are associated with higher incidence.
Objective:
The objective of the present study was to observe the histopathological pattern of intra-abdominal tumors in children less than 16 years.
Design:
This is a descriptive study.
Place And Duration Of Study:
The study was carried out at the Department of Histopathology, Children's Hospital and the Institute of Child Health and King Edward Medical College, Lahore, over a period of 5 years, from January 1997 to December 2002.
Subjects And Methods:
The histopathological and demographic data of 264 intra-abdominal tumors of both the sexes under 16 years of age was collected and analyzed to determine the various morphological types of intra-abdominal tumors in relation to age and sex.
Results:
Neuroblastoma was the most common tumor constituting 29.6% of all cases, followed by Wilms' tumor (25.1%). Others were non-Hodgkins lymphomas (15.5%), germ cell tumors and hepatoblastoma (9%) each, rhabdomyosarcoma (4.4%), hepatocellular carcinoma (1.4%) and miscellaneous (6%). Majority of the patients (77.2%) were under 5 years of age. The male to female ratio was 1.1:0.9.
Conclusion:
Intra-abdominal tumors are more common in males. Most of the tumors were noted in children less than 5 years of age.
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