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Published on: January 27, 2010
Metoclopramide induced akathisia during cesarean section
1Department of Anesthesia, Kaplan Medical Center, Rehovot, Israel. yico@internet-zahav.net
A rare case of akathisia, a movement disorder, occurred after metoclopramide use for nausea during cesarean delivery. This review covers prevention and treatment strategies for this adverse drug reaction.
Area of Science:
- Obstetrics and Gynecology
- Clinical Pharmacology
- Neurology
Background:
- Metoclopramide is commonly used to manage nausea and vomiting.
- Cesarean sections are a frequent obstetric procedure.
- Akathisia is a potential adverse effect of dopamine-blocking agents.
Purpose of the Study:
- To report a case of akathisia following metoclopramide administration.
- To review the literature on metoclopramide-induced akathisia.
- To discuss prevention and treatment options.
Main Methods:
- Case report.
- Literature review using relevant databases.
Main Results:
- A patient developed akathisia after receiving 2.5 mg of metoclopramide for nausea during a cesarean section.
- Literature search identified akathisia as a known, albeit uncommon, side effect of metoclopramide.
Conclusions:
- Akathisia is a possible adverse effect of metoclopramide, even at low doses.
- Awareness of this side effect is crucial for obstetricians.
- Management strategies for akathisia should be considered in clinical practice.
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