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Updated: Aug 9, 2026
Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction
Published on: March 7, 2013
[Postoperative complications after orthotopic liver transplantation: clinical analysis of 18 cases]
Shu-ying Su1, Huan-wei Chen, Zuo-jun Zhen
1Department of Hepatobiliary Surgery, First People's Hospital of Foshan, Foshan 528000, China.
Objective:
To investigate experience in diagnosis and treatment of postoperative complications in patients undergoing orthotopic liver transplantation (OLT).
Methods:
Complications, treatment and management following liver transplantation in 16 cases were analyzed retrospectively.
Results:
Of 16 patients, 5 patients had advanced liver cirrhosis, 7 primary liver carcinoma, 1 liver failure after hepatectomy for liver cancer, 1 Wilson's disease, 1 chronic renal failure and liver cirrhosis and 1 acute live failure. Twelve patients survived, the longest survival was 4 years. Complications following OLT included: intra-abdominal bleeding in 3 cases, intracerebral vascular lesions in 2, pulmonary infection in 6, adult respiratory distress syndrome in 2, suprahepatic inferior vena caval occlusion in 2, hepatic artery thrombus in 1 case, bile duct stone or sludge in 3, bile leakage in 1 case, acute rejection in 2, chronic rejection in 2, acute renal failure in 2. Six patients died during perioperative period, one patient died of intracerebral bleeding, one from adult respiratory distress syndrome, one of acute renal failure one of hepatic artery thrombus, one of acute rejection and one of liver failure.
Conclusions:
Proper prevention and treatment can effectively reduce complications following OLT during perioperative period. The timely diagnosis, treatment and prophylactics are necessary to prevent these complications.
