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Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
What is the maximum duration to perform the hemorheological measurement for the human and mammals
Jianbao Zhang1, Xiaojun Zhang, Nanlin Wang
1Department of Physics, the Fourth Military Medical University, Xi'an 710032, China. zhangyy@fmmu.edu.cn
Abstract:
The hemorheological performance of mammals and human will change with the time after the blood is withdraw from the subject. The whole blood apparent viscosity, erythrocyte deformability and aggregation of some mammals and human were measured. Our results showed that the hemorheological characteristics of mice, rats, guinea pigs, dogs and human began to change respectively after the threshold time of 0.5, 1, 3, 7, 12 h when the blood were stored in vitro. Moreover there exist a relationship: t=3.18W(0.32) between the threshold time (t) and the animal weight (W) and the related coefficient is 0.992.

