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Updated: Aug 22, 2026

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
Published on: August 2, 2012
Expression of molecular chirality and two-dimensional supramolecular self-assembly of chiral, racemic, and achiral
Wael Mamdouh1, Hiroshi Uji-I, Andrés E Dulcey
1Department of Chemistry, Laboratory of Photochemistry and Spectroscopy, Katholieke Universiteit Leuven, Celestijnenlaan 200-F, 3001 Leuven, Belgium.
Abstract:
We have investigated the two-dimensional ordering of chiral and achiral monodendrons at the liquid-solid interface. The chiral molecules self-assemble into extended arrays of dimers. As expected, the R enantiomer forms the mirror image type pattern of the chiral two-dimensional structure formed by the S enantiomer. A racemic mixture applied from solution onto the substrate undergoes spontaneous segregation: the enantiomers separate on the surface and appear in different domains. In contrast to the chiral molecules, the achiral analogue self-assembles into cyclic tetramers. Moreover, the pattern formed by the achiral molecule strongly depends on the solvent used. In the case of 1-phenyloctane, solvent molecules are coadsorbed in a 2:1 (dendron:solvent) ratio whereas in 1-octanol, no solvent molecules are coadsorbed. By the appropriate solvent choice, the distance between the potential "supramolecular containers" can be influenced.
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