Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sorting mesoscopic objects with periodic potential landscapes: optical fractionation.

K Ladavac1, K Kasza, D G Grier

  • 1Department of Physics, James Franck Institute and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, USA.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|August 25, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Technical note: characterizing individual milk fat globules with holographic video microscopy.

Journal of dairy science·2008
Same author

Phase II trial of oxaliplatin, leucovorin and fluorouracil in patients with advanced carcinoma of the esophagus.

Annals of oncology : official journal of the European Society for Medical Oncology·2005
Same author

Impact of disease burden at time of allogeneic stem cell transplantation in adults with acute myeloid leukemia and myelodysplastic syndromes.

Bone marrow transplantation·2005
Same author

The pathophysiology of HOX genes and their role in cancer.

The Journal of pathology·2005
Same author

A phase II study of oxaliplatin and paclitaxel in patients with advanced non-small-cell lung cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2004
Same author

A phase II trial of the epothilone B analog, BMS-247550, in patients with previously treated advanced colorectal cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2004

Objects driven through modulated potentials can be deflected. Object size significantly impacts kinetic locking, enabling size-based sorting via optical fractionation with holographic optical tweezers.

Area of Science:

  • Physics
  • Soft Matter Physics
  • Nanotechnology

Background:

  • Viscously damped objects driven through periodic potentials can exhibit complex dynamics.
  • Kinetic locking and deflection are observed phenomena in driven systems.
  • Controlling mesoscopic object behavior is crucial for various applications.

Purpose of the Study:

  • To investigate the influence of object size on kinetic locking in modulated potential energy landscapes.
  • To demonstrate a size-dependent sorting mechanism for mesoscopic objects.
  • To introduce optical fractionation as a continuous sorting technique.

Main Methods:

  • Simulating or experimentally driving viscously damped objects through a periodically modulated potential energy landscape.
  • Analyzing the conditions leading to kinetic locking and deflection.

Related Experiment Videos

  • Implementing the technique using an array of holographic optical tweezers.

    • Main Results:

    • The threshold for kinetic locking demonstrates an exceptionally strong dependence on object size.
    • Objects can be deflected away from the driving direction based on their size.
    • Successful sorting of mesoscopic objects was achieved using the developed technique.

    Conclusions:

    • Object size is a critical parameter determining kinetic locking in driven periodic potentials.
    • Optical fractionation offers a continuous and optimized method for sorting mesoscopic objects based on size.
    • Holographic optical tweezers provide a versatile platform for implementing optical fractionation.