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Published on: December 29, 2015
Ice as a reservoir for pathogenic human viruses: specifically, caliciviruses, influenza viruses, and enteroviruses
Alvin W Smith1, Douglas E Skilling, John D Castello
1Laboratory for Calicivirus Studies, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA.
Abstract:
Hundreds of isolates of viable bacteria and fungi have been recovered from ancient ice and permafrost. Evidence supports the hypothesis that viral pathogens also are preserved in ice repositories, such as glaciers, ice sheets, and lake ice. Proof may depend upon narrowing the search by applying specific criteria, which would target candidate viruses. Such criteria include viral pathogens likely to occur in great abundance, likely to be readily transported into ice, and then participate in ongoing disease cycles suggestive of their having been deposited in and subsequently released from ice. Caliciviruses, influenza A, and some enteroviruses appear to satisfy all three criteria. Environmental ice appears to be an important abiotic reservoir for pathogenic microbes. World health and eradication of specific pathogens could be affected by this huge reservoir.
Insights
Ancient ice and permafrost harbor viable microbes, including potential viral pathogens. These environmental ice reservoirs pose risks to global health and pathogen eradication efforts.
Area of Science:
- Microbiology
- Virology
- Environmental Science
Background:
- Viable bacteria and fungi have been recovered from ancient ice and permafrost.
- Evidence suggests viral pathogens may also be preserved in ice repositories like glaciers and lake ice.
Purpose of the Study:
- To explore the hypothesis that viral pathogens are preserved in ice.
- To identify criteria for targeting candidate viruses in ice repositories.
Main Methods:
- Reviewing criteria for viral pathogen survival and deposition in ice.
- Evaluating specific viruses (caliciviruses, influenza A, enteroviruses) against these criteria.
Main Results:
- Caliciviruses, influenza A, and certain enteroviruses meet the criteria for viruses preserved in ice.
- Environmental ice is identified as a significant abiotic reservoir for pathogenic microbes.
Conclusions:
- Environmental ice acts as a substantial reservoir for potentially infectious viral pathogens.
- The vast microbial content of ice could impact global health and pathogen eradication strategies.
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