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Steroid responsive late deterioration in Cryptococcus neoformans variety gattii meningitis
Margaret Lane1, John McBride, John Archer
1Department of Infectious Diseases, Cairns Base Hospital, and School of Medicine, James Cook University, Queensland, Australia.
Neurology
|August 25, 2004
Abstract:
The authors describe the clinical course of Cryptococcus neoformans variety gattii infection in a young immunocompetent man who had a late deterioration characterized by headaches, subarachnoid inflammation, hydrocephalus, and stroke that reproducibly responded to steroids. These findings, in combination with declining markers of CSF infection, are consistent with the late deterioration being caused by sterile arachnoiditis rather than ongoing infection.