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Updated: Aug 22, 2026

Co-Culture In Vitro Systems to Reproduce the Cancer-Immunity Cycle
Published on: June 7, 2024
An immunogenic process leading to cancer in the context of immunodeficiency
Richard Hamelin1, Claire Borie, Martine Raphaël
1INSERM U434, Paris, France. richard.hamelin@cephb.fr
Abstract:
Colorectal MSI tumors are associated with an increased immune response. On the other hand, immunodeficient patients are more prone to lymphomas with the MSI phenotype. These facts are of wide interest in understanding the complex link between immunity and cancer, particularly of the MSI phenotype. Specific attention to the host immune system should thus be considered in the treatment of patients with MSI tumors.
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