Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary midbrain germinoma.

S Ben Amor1, K Siddiqui, S Baessa

  • 1Department of Neurosciences, King Faisal Specialist Hospital & RC, Jeddah, Kingdom of Saudi Arabia. benamor@healthgulf.com

British Journal of Neurosurgery
|August 26, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An international 20 country patient and physician survey of the usability and acceptability of Stepped Care pathway in Parkinson's disease.

Scientific reports·2025
Same author

[Penetrating ocular injuries in children: Clinical profile and psychosocial impact in southern Tunisia].

Journal francais d'ophtalmologie·2025
Same author

UNITY: A low-field magnetic resonance neuroimaging initiative to characterize neurodevelopment in low and middle-income settings.

Developmental cognitive neuroscience·2024
Same author

Bilateral serous retinal detachment as a manifestation of acute bilineal leukemia: Case report.

Journal francais d'ophtalmologie·2023
Same author

Multimodal Biomarkers That Predict the Presence of Gleason Pattern 4: Potential Impact for Active Surveillance.

The Journal of urology·2023
Same author

Instruments to assess appropriateness of hip and knee arthroplasty: a systematic review.

Osteoarthritis and cartilage·2023

Intracranial germinomas are rare midbrain tumors. This case highlights the need for biopsy in diagnosing these challenging lesions, which respond well to treatment.

Area of Science:

  • Neuro-oncology
  • Pediatric oncology

Background:

  • Intracranial germinomas are rare tumors, with primary midbrain origin being exceptionally uncommon.
  • Only one previous case of primary midbrain germinoma has been documented in medical literature.

Observation:

  • A 15-year-old male presented with symptoms including headache, diplopia, unsteadiness, and personality changes.
  • Brain Magnetic Resonance Imaging (MRI) revealed a heterogeneous lesion within the midbrain, with the pineal region unaffected.
  • Initial differential diagnoses considered brain-stem glioma, metastasis, and lymphoma.

Findings:

  • Stereotactic biopsy confirmed the diagnosis of germinoma.
  • The patient demonstrated a positive response to chemotherapy and radiotherapy.

Related Experiment Videos

Implications:

  • Germinoma should be considered in the differential diagnosis of midbrain lesions.
  • Accurate preoperative diagnosis of midbrain germinoma is challenging, underscoring the necessity of biopsy.
  • Early diagnosis and treatment lead to favorable outcomes for patients with midbrain germinoma.